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Catharanthine [2468-21-5]

HY-N0252
MedChem Express
CAS Number2468-21-5
Product group Chemicals
Estimated Purity99.65
Molecular Weight336.43
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Catharanthine [2468-21-5]
  • Delivery Days Customer
    10
  • CAS Number
    2468-21-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.65
  • Molecular Formula
    C21H24N2O2
  • Molecular Weight
    336.43
  • Scientific Description
    Catharanthine ((+)-3,4-Didehydrocoronaridine), a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca2+ channel (VOCC). Catharanthine has IC50s of 220 microM and 8 microM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine lowers blood pressure (BP), heart rate (HR). Catharanthine has anti-cancer activity[1][2].
  • SMILES
    O=C([C@@]12C3=C(CC[N@](C4)[C@]1([H])C(CC)=C[C@@]4([H])C2)C5=CC=CC=C5N3)OC
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200