Catharanthine (Tartrate)

MedChem Express

Catharanthine (Tartrate) [4168-17-6]

5

4168-17-6

Research Use Only

98.88

C25H30N2O8

486.51

Catharanthine ((+)-3,4-Didehydrocoronaridine) Tartrate, a constituent of anticancer vinca alkaloids, inhibits voltage-operated L-type Ca 2+ channel (VOCC) . Catharanthine Tartrate has IC 50 s of 220 microM and 8 microM for VOCC currents in cardiomyocytes and vascular smooth muscle cells (VSMCs), respectively. Catharanthine Tartrate lowers blood pressure (BP), heart rate (HR). Catharanthine Tartrate has anti-cancer activity [1] [2] .

O=C([C@@]1(C2=C3C(C=CC=C4)=C4N2)[C@](C(CC)=C5)([H])[N@](CC3)C[C@]5([H])C1)OC.O[C@@H](C(O)=O)[C@H](C(O)=O)O

2°C to 8°C

12352200