Cathepsin C-IN-5 [2825567-97-1]

MedChem Express

Cathepsin C-IN-5 [2825567-97-1]

10

2825567-97-1

Research Use Only

95.70

C21H17ClN6OS

436.92

Cathepsin C-IN-5 (compound SF38) is a potent, selective and orally active Cathepsin C inhibitor with IC50s of 59.9 nM, 4.26 microM, >5 microM, >5 microM, >5 microM for Cat C, Cat L, Cat S, Cat B, Cat K, respectively. Cathepsin C-IN-5 inhibits the Cat C activity in bone marrow and blood. Cathepsin C-IN-5 decreases the activation of NSPs (neutrophil serine proteases). Cathepsin C-IN-5 shows anti-inflammatory activity[1].

CC(NC1=CC=CC(NC2=C(C=NC(NC3=NC=C(C=C3)C4=CSC=C4)=N2)Cl)=C1)=O

2°C to 8°C

12131703