Cathepsin F blocking peptide
GTX89526-PEP
Product group Proteins / Signaling Molecules
Overview
- SupplierGeneTex
- Product NameCathepsin F blocking peptide
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionCathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202