
Western blot All lanes: CATSPER2 antibody at 4microg/ml Lane 1: Jurkat whole cell lysate Lane 2: HepG2 whole cell lysate Lane 3: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 63, 62, 49, 24 kDa Observed band size: 63 kDa
CATSPER2 Antibody
CSB-PA842731LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCATSPER2
Overview
- SupplierCusabio
- Product NameCATSPER2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID117155
- Target nameCATSPER2
- Target descriptioncation channel sperm associated 2
- Target synonymscation channel sperm-associated protein 2, sperm ion channel
- HostRabbit
- IsotypeIgG
- Protein IDQ96P56
- Protein NameCation channel sperm-associated protein 2
- Scientific DescriptionVoltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161



