Cav beta 4 antibody [C3], C-term

GeneTex

Cav beta 4 antibody [C3], C-term

9

WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CACNB4

calcium voltage-gated channel auxiliary subunit beta 4

CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6, voltage-dependent L-type calcium channel subunit beta-4, calcium channel voltage-dependent subunit beta 4, dihydropyridine-sensitive L-type, calcium channel beta-4 subunit

Rabbit

IgG

Voltage-dependent L-type calcium channel subunit beta-4

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203