Western Blot analysis of Human fetal muscle and fetal lung tissue, Human leiomyosarcoma tissue, Mouse lung and heart tissue, NIH/3T3 cell using CAV1 Polyclonal Antibody at dilution of 1:550
Western Blot analysis of Human fetal muscle and fetal lung tissue, Human leiomyosarcoma tissue, Mouse lung and heart tissue, NIH/3T3 cell using CAV1 Polyclonal Antibody at dilution of 1:550
CAV1 Polyclonal Antibody
E-AB-13048
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCAV1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
- UNSPSC12352203