
WB analysis of rat heart membrane lysate using GTX16608 Cav1.2 antibody preincubated with or without immunogen peptide. Dilution : 1:200
Cav1.2 antibody
GTX16608
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCACNA1C
Overview
- SupplierGeneTex
- Product NameCav1.2 antibody
- Delivery Days Customer7
- Antibody SpecificityThe antibody recognizes mouse CaV1.2, splice variants P22002-4 and P22002-5 of rat CaV1.2 and splice variant P15381-4 of rabbit CaV1.2.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.8 mg/ml
- ConjugateUnconjugated
- Gene ID775
- Target nameCACNA1C
- Target descriptioncalcium voltage-gated channel subunit alpha1 C
- Target synonymsCACH2; CACN2; CACNL1A1; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; CaV1.2; CCHL1A1; DHPR, alpha-1 subunit; LQT8; TS; TS. LQT8; voltage-dependent L-type Ca2+ channel alpha 1 subunit; voltage-dependent L-type calcium channel subunit alpha-1C; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
- HostRabbit
- IsotypeIgG
- Protein IDQ13936
- Protein NameVoltage-dependent L-type calcium channel subunit alpha-1C
- Scientific DescriptionThis gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1alpha Inhibition. Osuru HP et al., 2022, Front Cardiovasc MedRead more