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WB analysis of rat heart membrane lysate using GTX16608 Cav1.2 antibody preincubated with or without immunogen peptide. Dilution : 1:200
WB analysis of rat heart membrane lysate using GTX16608 Cav1.2 antibody preincubated with or without immunogen peptide. Dilution : 1:200
WB analysis of rat heart membrane lysate using GTX16608 Cav1.2 antibody preincubated with or without immunogen peptide. Dilution : 1:200

Cav1.2 antibody

GTX16608
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCACNA1C
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cav1.2 antibody
  • Delivery Days Customer
    7
  • Antibody Specificity
    The antibody recognizes mouse CaV1.2, splice variants P22002-4 and P22002-5 of rat CaV1.2 and splice variant P15381-4 of rabbit CaV1.2.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.8 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID775
  • Target name
    CACNA1C
  • Target description
    calcium voltage-gated channel subunit alpha1 C
  • Target synonyms
    CACH2; CACN2; CACNL1A1; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; CaV1.2; CCHL1A1; DHPR, alpha-1 subunit; LQT8; TS; TS. LQT8; voltage-dependent L-type Ca2+ channel alpha 1 subunit; voltage-dependent L-type calcium channel subunit alpha-1C; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ13936
  • Protein Name
    Voltage-dependent L-type calcium channel subunit alpha-1C
  • Scientific Description
    This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. [provided by RefSeq, Oct 2012]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1alpha Inhibition. Osuru HP et al., 2022, Front Cardiovasc Med
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