Cavalpha2delta1&NET-IN-2 [2143586-17-6]
HY-148863
CAS Number2143586-17-6
Product group Chemicals
Molecular Weight438.55
Overview
- SupplierMedChem Express
- Product NameCavalpha2delta1&NET-IN-2 [2143586-17-6]
- Delivery Days Customer10
- CAS Number2143586-17-6
- CertificationResearch Use Only
- Molecular FormulaC22H26N6O2S
- Molecular Weight438.55
- Scientific DescriptionCavalpha2delta1&NET-IN-2 (Compound 45CS) is a dual inhibitor of the alpha2delta-1 subunit of voltage-gated calcium channels (Cavalpha2delta-1) and the norepinephrine transporter (NET). Cavalpha2delta1&NET-IN-2 inhibits Cavalpha2delta-1 with a Ki of 454 nM. Cavalpha2delta1&NET-IN-2 inhibits NET with a Ki of 59 nM and IC50 of 7 nM. Cavalpha2delta1&NET-IN-2 can be used for research of pain[1].
- SMILESO=C1N(CCN(C2=NC(N)=NC=C21)C)C3=CC(O[C@H](C4=CC=CS4)CCNC)=CC=C3
- UNSPSC12131703