CAY10526 [938069-71-7]
HY-118119
CAS Number938069-71-7
Product group Chemicals
Estimated Purity99.12
Molecular Weight311.16
Overview
- SupplierMedChem Express
- Product NameCAY10526 [938069-71-7]
- Delivery Days Customer10
- CAS Number938069-71-7
- CertificationResearch Use Only
- Estimated Purity99.12
- Molecular FormulaC12H7BrO3S
- Molecular Weight311.16
- Scientific DescriptionCAY10526 is a specific microsomal PGE2 synthase-1 (mPGES1) inhibitor. CAY10526 inhibits PGE2 production through the selective modulation of mPGES1 expression but does not affect COX-2. CAY10526 significantly suppresses tumor growth and increases apoptosis in melanoma xenografts. CAY10526 reduces BCL-2 and BCL-XL (anti-apoptotic) protein levels and increases BAX and BAK (pro-apoptotic) as well as cleaved caspase 3 levels. CAY10526 inhibits cell viability (IC50[1].
- SMILESO=C1C(Br)=C(C(O1)O)C2=CC3=CC=CC=C3S2
- Storage Instruction2°C to 8°C
- UNSPSC12352200
![CAY10526 [938069-71-7]](https://www.targetmol.com/group3/M00/37/DC/CgoaEGayUsuEfDdbAAAAAF1YH-A864.png)