CAY10573 [853652-40-1]

TargetMol Chemicals

CAY10573 [853652-40-1]

44

853652-40-1

Research Use Only

CAY10573

C33H31NO5

521.6

The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARalpha, gamma, and delta with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARalpha, gamma, and delta with EC50 values of 8, 70, and 500 nM, respectively. CAY10573 demonstrates stronger binding and functional activity for PPARgamma than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).

3 years

C(CC)C=1C2=C(C=C(C(=O)C3=CC=CC=C3)C=C2)C=CC1OCCCOC=4C=C5C(=CC4)N(CC(O)=O)C=C5

-20°C

12352200