CAY10602 [374922-43-7]

TargetMol Chemicals

CAY10602 [374922-43-7]

9

374922-43-7

Chemical

Research Use Only

CAY10602

98.87%

C22H15FN4O2S

418.44

CAY10602 is a SIRT1 activator derived from high throughput screening for compounds that enhance SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays indicate that CAY10602 dose-dependently suppresses NF-kappaB-dependent induction of TNF-alpha by lipopolysaccharide in THP-1 cells, achieving approximately 75% inhibition at 60 microM without cytotoxicity.

3 years

Nc1c(c2nc3ccccc3nc2n1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1

-20°C

12352200