CB 3705 [5854-11-5]
HY-122045
CAS Number5854-11-5
Product group Chemicals
Molecular Weight439.42
Overview
- SupplierMedChem Express
- Product NameCB 3705 [5854-11-5]
- Delivery Days Customer999
- CAS Number5854-11-5
- CertificationResearch Use Only
- Molecular FormulaC21H21N5O6
- Molecular Weight439.42
- Scientific DescriptionCB 3705 is a dihydrofolate reductase (DHFR) and thymidylate synthetase (TS) inhibitor. CB 3705 inhibits L1210 cells and mutant L1210 cell line (L1210:C15) with ID50s of 4.77 microM and 408 microM, respectively[1][2].
- SMILESO=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NCC2=CC3=C(NC(N)=NC3=O)C=C2)C=C1)=O
- UNSPSC12352200