CB-6644 [2316817-88-4]
T10693
CAS Number2316817-88-4
Product group Chemicals
Molecular Weight573.06
Overview
- SupplierTargetMol Chemicals
- Product NameCB-6644 [2316817-88-4]
- Delivery Days Customer4
- CAS Number2316817-88-4
- CertificationResearch Use Only
- Chemical NameCB-6644
- Molecular FormulaC29H34ClFN4O5
- Molecular Weight573.06
- Scientific DescriptionCB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex. It specifically interacts with RUVBL1/2 in cancer cells and blocks the ATPase activity of RUVBL1/2 with a half-maximal inhibitory concentration (IC50) of 15 nM[1].
- Shelf life instruction3 years
- SMILESCCOc1cc(F)c(Cl)cc1C(=O)NCC(C)(C)CC(=O)Nc1c(COC)n2CCCc3ccccc3-n2c1=O
- Storage Instruction-20°C
- UNSPSC12352200
References
- Sun F, Wang X, Hu J, et al. RUVBL1 promotes enzalutamide resistance of prostate tumors through the PLXNA1-CRAF-MAPK pathway. Oncogene. 2022,41(23):3239-3250. doi: 10.1038/s41388-022-02332-8Read this paper
MSDS
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