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CB-6644 [2316817-88-4]

CB-6644 [2316817-88-4]

T10693
TargetMol Chemicals
CAS Number2316817-88-4
DownloadMSDS
Product group Chemicals
Molecular Weight573.06
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CB-6644 [2316817-88-4]
  • Delivery Days Customer
    4
  • CAS Number
    2316817-88-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CB-6644
  • Molecular Formula
    C29H34ClFN4O5
  • Molecular Weight
    573.06
  • Scientific Description
    CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex. It specifically interacts with RUVBL1/2 in cancer cells and blocks the ATPase activity of RUVBL1/2 with a half-maximal inhibitory concentration (IC50) of 15 nM[1].
  • Shelf life instruction
    3 years
  • SMILES
    CCOc1cc(F)c(Cl)cc1C(=O)NCC(C)(C)CC(=O)Nc1c(COC)n2CCCc3ccccc3-n2c1=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • RUVBL1 promotes enzalutamide resistance of prostate tumors through the PLXNA1-CRAF-MAPK pathway. Sun F et al., 2022 Jun, Oncogene
    Read more

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