CB1954

AbMole BioScience

CB1954

9

21919-05-1

Research Use Only

C9H8N4O5

252.18

CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent. It can be activated by NAD(P)H quinone oxidoreductase 2.

NC(=O)C1=C(C=C(C(=C1)N2CC2)[N+]([O-])=O)[N+]([O-])=O

12352200