Cbl-b-IN-1

MedChem Express

Cbl-b-IN-1 [2368841-84-1]

10

2368841-84-1

Research Use Only

99.66

C29H34N6O2

498.62

Cbl-b-IN-1 (Example 519) is an inhibitor of Cbl-b, with an IC50 of less than 100 nM. Cbl-b-IN-1 can promote the secretion of cytokines such as IL-2, IFN-gamma, and TNF-alpha, facilitate T cell activation, and enhance the TCR signaling pathway. Cbl-b-IN-1 can be used in research on immunomodulation[1][2].

O=C(C1=NC(C2CC2)=CC(CN(CC3)CC43CC4)=C1)NC5=CC=CC(C6(CC7=NN=CN7C)COC6)=C5

-20°C,2°C to 8°C

12352200