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CBL-B TR-FRET Assay Kit

CBL-B TR-FRET Assay Kit

Research Use Only
79575
BPS Bioscience
Product group Assays
Price on request
Packing Size
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    CBL-B TR-FRET Assay Kit
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    Human Casitas B-lineage lymphoma proto-oncogene b (CBL-B) is an E3 ubiquitinprotein ligase that functions as a negative regulator of T-cell activation. It is a promising drug target in cancer immunotherapy. The CBL-B TR-FRET Assay Kit is designed to measure CBL-B auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled Ubiquitin and a terbium-labeled anti-CBL-B antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps, making it especially suitable for high throughput screening applications.
  • UNSPSC
    41116133

References

  • Jeon, M.S., et al., Immunity. 2004, 21(2): 167-177
  • Chiang, Y.J. et al., Nature. 2000, 403: 216-220

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