CC0651 [1319207-44-7]

MedChem Express

CC0651 [1319207-44-7]

10

1319207-44-7

Research Use Only

99.03

C20H21Cl2NO6

442.29

CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 microM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis.

ClC1=CC(Cl)=CC(C2=CC=C(C=C2)C[C@@H]([C@@H]([C@H](C(O)=O)O)O)NC(COC)=O)=C1

-20°C,2°C to 8°C

12352200