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ProductsBack/CC214-2 [1228012-18-7]

CC214-2 [1228012-18-7]

HY-145931
MedChem Express
CAS Number1228012-18-7
Product group Chemicals
Estimated Purity98.41
Molecular Weight383.44
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Overview

  • Supplier
    MedChem Express
  • Product Name
    CC214-2 [1228012-18-7]
  • Delivery Days Customer
    10
  • CAS Number
    1228012-18-7
  • Certification
    Research Use Only
  • Estimated Purity
    98.41
  • Molecular Formula
    C20H25N5O3
  • Molecular Weight
    383.44
  • Scientific Description
    CC214-2 is an oral active and selective mTOR kinase inhibitor. CC214-2 targets to both of mTORC1 (pS6) and mTORC2 (pAktS473). CC214-2 induces autophagy, which is a potential target for host-directed therapy (HDT) in tuberculosis. CC214-2 exhibits synergistic bactericidal and sterilizing activity agasinst tuberculosis (TB), and shortens the treatment duration. CC214-2 also inhibits Rapamycin (HY-10219)-resistant signaling and the growth of glioblastomas in vitro and in vivo[1][2].
  • SMILES
    O=C1N=C2NC=C(C3=CC=C(C(C)(C)O)N=C3)N=C2N(CC4CCOCC4)C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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