CCB02 [2100864-57-9]

MedChem Express

CCB02 [2100864-57-9]

10

2100864-57-9

Research Use Only

99.93

C14H9N3O

235.24

CCB02 is a selective CPAP-tubulin interaction inhibitor, binding to tubulin and competing for the CPAP binding site of beta-tubulin, with an IC50 of 689 nM, and shows potent anti-tumor activity. CCB02 shows no inhibition on the cell cycle- and centrosome-related kinases, or the phosphorylation status of Aurora A, Plk1, Plk2, CDK2, and CHK1[1].

N#CC1=C(OC)N=CC2=CC3=CC=CC=C3N=C12

-20°C

12352200