IHC-P analysis of human brain tissue using GTX85268 CCDC134 antibody. Working concentration : 2.5 microg/ml
IHC-P analysis of human brain tissue using GTX85268 CCDC134 antibody. Working concentration : 2.5 microg/ml
CCDC134 antibody
GTX85268
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCCDC134
Overview
- SupplierGeneTex
- Product NameCCDC134 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID79879
- Target nameCCDC134
- Target descriptioncoiled-coil domain containing 134
- Target synonymscoiled-coil domain-containing protein 134
- HostRabbit
- IsotypeIgG
- Protein IDQ9H6E4
- Protein NameCoiled-coil domain-containing protein 134
- Scientific DescriptionThe coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203