CCG-271423 [2750413-88-6]

MedChem Express

CCG-271423 [2750413-88-6]

10

2750413-88-6

Research Use Only

C28H26N4O3

466.53

CCG-271423 is a potent and selective GRK5 inhibitor with IC50 values of 0.0021 microM and 44 microM for GRK5 and GRK2, respectively. CCG-271423 inhibits cardiomyocyte contractility and decreases in Ca2+ transience[1]. CCG-271423 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C(/C(C1=C2)=C\C3=C(C(C(NCC#C)=O)=C(N3)C)C)NC1=CC=C2C(N[C@@H](C4=CC=CC=C4)C)=O

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