CCG-50014 (Standard) [883050-24-6]

MedChem Express

CCG-50014 (Standard) [883050-24-6]

5

883050-24-6

Research Use Only

316.35

CCG-50014 (Standard) is the analytical standard of CCG-50014. This product is intended for research and analytical applications. CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site[1]. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test[2].

O=C(N1CC2=CC=C(F)C=C2)N(C3=CC=C(C)C=C3)SC1=O

12352100