Bio-Connect

CCL14/HCC-1 ELISA Kit (Human)

OKBB00501
Aviva Systems Biology
ReactivityHuman
Product group Assays
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Overview

  • Supplier
    Aviva Systems Biology
  • Product Name
    CCL14/HCC-1 ELISA Kit (Human)
  • Delivery Days Customer
    23
  • Application Supplier Note
    Assay Methodology: Quantitative Sandwich Immunoassay
  • Applications
    ELISA
  • Assay Detection Range
    15.6 pg/ml - 1,000 pg/ml
  • Assay Sensitivity
    <10 pg/ml
  • Assay Test Principle
    Avivas human CCL14 ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for CCL14 has been precoated onto 96-well plates. Standards(E.coli, T20-N93) and test samples are...
  • Assay Time
    2.5 Hours
  • Certification
    Research Use Only
  • Scientific Description
    Chemokine (C-C motif) ligand 14 (CCL14) is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is processed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL14 activates monocytes, but does not induce their chemotaxis. In addition, HCC-1 enhanced the proliferation of CD34+ myeloid progenitor cells. It was as effective as MIP-1 alpha, but about 100-fold less potent. Human CCL14 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41116100
  • Species
    Human