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CCR1 antibody

GTX70509
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCCR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CCR1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 5 microg/ml. IHC-P: 5 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1230
  • Target name
    CCR1
  • Target description
    C-C motif chemokine receptor 1
  • Target synonyms
    CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1, C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, LD78 receptor, MIP-1alpha-R, RANTES receptor, RANTES-R, chemokine (C-C motif) receptor 1, macrophage inflammatory protein 1-alpha receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP32246
  • Protein Name
    C-C chemokine receptor type 1
  • Scientific Description
    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Prognostic significance of expression of CCL5/RANTES receptors in patients with gastric cancer. Sugasawa H et al., 2008 Apr 1, J Surg Oncol
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  • Gastric cancer cells exploit CD4+ cell-derived CCL5 for their growth and prevention of CD8+ cell-involved tumor elimination. Sugasawa H et al., 2008 Jun 1, Int J Cancer
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