CCR10 antibody [HL2853]

GeneTex

CCR10 antibody [HL2853]

9

ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL2853

1 mg/ml

Unconjugated

CCR10

C-C motif chemokine receptor 10

GPR2, C-C chemokine receptor type 10, C-C CKR-10, CC chemokine receptor 10, CC-CKR-10, CCR-10, G-protein coupled receptor 2, chemokine (C-C motif) receptor 10

Rabbit

IgG

C-C chemokine receptor type 10

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203