CCR2 antagonist 4

MedChem Express

CCR2 antagonist 4 [226226-39-7]

10

226226-39-7

Research Use Only

99.89

C21H21ClF3N3O2

439.86

CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC 50 s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC 50 of 24 nM [1] .

O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3

-20°C,2°C to 8°C

12352200