CCR2 antagonist 4 (hydrochloride)

MedChem Express

CCR2 antagonist 4 (hydrochloride)

10

1313730-14-1

Research Use Only

99.91

C21H22Cl2F3N3O2

476.32

CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM[1].

O=C(NCC(N[C@H]1CN(CC2=CC=C(Cl)C=C2)CC1)=O)C3=CC=CC(C(F)(F)F)=C3.[H]Cl

2°C to 8°C

12352200