CCR4-351

MedChem Express

CCR4-351 [2174938-70-4]

5

2174938-70-4

Research Use Only

98.95

C24H27Cl2N7O

500.42

CCR4-351 is an orally active, potent and selective CCR4 antagonist. CCR4-351, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4-351 has antitumor activity [1] .

[H][C@@]1(CCCN(C1)CCO)C2CN(C2)C3=CN=C(C4=N3)C(C#N)=NN4[C@H](C)C5=CC=C(C=C5Cl)Cl

2°C to 8°C

12352200