Bio-Connect

CCR5 peptide

GTX27876
GeneTex
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    GeneTex
  • Product Name
    CCR5 peptide
  • Delivery Days Customer
    9
  • Application Supplier Note
    The peptide is used for blocking the activity of anti-CCR5 (GTX27346). Incubatingthe peptide with equal volume of antibody for 30 min at 37C usually completely blocks theactivity of anti-CCR5 in Western blotting.
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Concentration
    0.20 mg/ml
  • Conjugate
    Unconjugated
  • Scientific Description
    Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co receptor. The chemokine receptor CCR5 is one of the co receptors used by primary isolates of HIV1. Extracellular domains of CCR5 are important for HIV entry into the target cells.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202