CCR5 peptide

GeneTex

CCR5 peptide

9

The peptide is used for blocking the activity of anti-CCR5 (GTX27346). Incubatingthe peptide with equal volume of antibody for 30 min at 37C usually completely blocks theactivity of anti-CCR5 in Western blotting.

Neutralisation/Blocking

Research Use Only

0.20 mg/ml

Unconjugated

Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co receptor. The chemokine receptor CCR5 is one of the co receptors used by primary isolates of HIV1. Extracellular domains of CCR5 are important for HIV entry into the target cells.

-20°C

12352202