Bio-Connect

CCR5 Polyclonal Antibody

RD70555A
Reddot Biotech
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityMouse, Rat
TargetCcr5
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Reddot Biotech
  • Product Name
    CCR5 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.55 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID12774
  • Target name
    Ccr5
  • Target description
    chemokine (C-C motif) receptor 5
  • Target synonyms
    AM4-7; C-C chemokine receptor type 5; C-C CKR-5; CC-CKR-5; CCR-5; CD195; chemokine (C-C) receptor 5; Cmkbr; Cmkbr5; MIP-1 alpha receptor
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.
  • Reactivity
    Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203