CCR6 -VLP, Human (HEK293)

MedChem Express

CCR6 -VLP, Human (HEK293)

5

Research Use Only

CCR6

C-C motif chemokine receptor 6

BN-1, C-C CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22, C-C chemokine receptor type 6, G protein-coupled receptor 29, LARC receptor, chemokine (C-C motif) receptor 6, chemokine (C-C) receptor 6, chemokine receptor-like 3, seven-transmembrane receptor, lymphocyte, 22

C-C chemokine receptor type 6

The CCR6 protein is a receptor for CCL20 and increases intracellular calcium levels upon ligand binding. Notably, CCR6 also acts as a receptor for non-chemokine ligands such as beta-defensins (DEFB1, DEFB4, DEFB4A/B). CCR6 Protein-VLP, Human (HEK293) is the recombinant human-derived CCR6 protein, expressed by HEK293, with tag free.Formed in HEK293 cultures, these VLPs concentrate membrane proteins on the cell surface, producing high-concentration proteins ideal for immunization and antibody screening. Given the high immunogenicity of VLPs, the immunization protocol such as antigen dose, schedule, and adjuvant, requires optimization. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

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