CCR7 Ligand 1 [681514-83-0]

TargetMol Chemicals

CCR7 Ligand 1

114

681514-83-0

Chemical

Research Use Only

CCR7 Ligand 1

C22H29N5O5S

475.56

CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. This thiadiazole-dioxide ligand suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 microM.

3 years

CN(C)C(=O)c1c(C)ccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O

-20°C

12352200