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CCT241533 hydrochloride [1431697-96-9]

CCT241533 hydrochloride [1431697-96-9]

T10718L
TargetMol Chemicals
CAS Number1431697-96-9
Product group Chemicals
Molecular Weight478.95
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CCT241533 hydrochloride [1431697-96-9]
  • Delivery Days Customer
    10
  • CAS Number
    1431697-96-9
  • Certification
    Research Use Only
  • Chemical Name
    CCT241533 hydrochloride
  • Molecular Formula
    C23H28ClFN4O4
  • Molecular Weight
    478.95
  • Scientific Description
    CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).
  • Shelf life instruction
    3 years
  • SMILES
    Cl.COc1cc2nc(nc(N[C@@H]3CNC[C@H]3C(C)(C)O)c2cc1OC)-c1cc(F)ccc1O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Anderson VE, Walton MI, Eve PD, et al. CCT241533 is a potent and selective inhibitor of CHK2 that potentiates the cytotoxicity of PARP inhibitors. Cancer Res. 2011,71(2):463-72. doi: 10.1158/0008-5472.CAN-10-1252
    Read this paper