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ProductsBack/CD134 antibody [OX-40]

CD134 antibody [OX-40]

GTX42439
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityRat
TargetTnfrsf4
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD134 antibody [OX-40]
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 1/10-1/50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    OX-40
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID25572
  • Target name
    Tnfrsf4
  • Target description
    TNF receptor superfamily member 4
  • Target synonyms
    MRC OX40; Ox40; OX40 antigen; OX40L receptor; Tax-transcriptionally activated glycoprotein 1; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1
  • Host
    Mouse
  • Isotype
    IgG2b
  • Protein IDP15725
  • Protein Name
    Tumor necrosis factor receptor superfamily member 4
  • Scientific Description
    membrane-bound receptor, binds adaptor proteins Traf2 and Traf5; member of the tumor necrosis factor (TNF)-receptor superfamily [RGD, Feb 2006]
  • Reactivity
    Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • OX40 ligand fusion protein delivered simultaneously with the BCG vaccine provides superior protection against murine Mycobacterium tuberculosis infection. Snelgrove RJ et al., 2012 Mar 15, J Infect Dis
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  • Immune responses elicited in tertiary lymphoid tissues display distinctive features. Thaunat O et al., 2010 Jun 30, PLoS One
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  • T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells. Volovitz I et al., 2010 Sep, J Autoimmun
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  • The biological response modifier AM3 attenuates the inflammatory cell response and hepatic fibrosis in rats with biliary cirrhosis. Albillos A et al., 2010 Jul, Gut
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  • Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts. Giorgini A et al., 2007 Nov, J Leukoc Biol
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  • Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene. Cousins L et al., 2006 Nov, Gastroenterology
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  • Phenotypic characterization of regulatory CD4+CD25+ T cells in rats. Stephens LA et al., 2004 Feb, Int Immunol
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  • A critical role for OX40 in T cell-mediated immunopathology during lung viral infection. Humphreys IR et al., 2003 Oct 20, J Exp Med
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  • Cholera toxin promotes the induction of regulatory T cells specific for bystander antigens by modulating dendritic cell activation. Lavelle EC et al., 2003 Sep 1, J Immunol
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  • Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers. Walker LS et al., 1999 Oct 18, J Exp Med
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