CD137L / 4-1BBL / TNFSF9(CD137L/1547), CF740 conjugate, 0.1mg/mL

Biotium

CD137L / 4-1BBL / TNFSF9(CD137L/1547), CF740 conjugate, 0.1mg/mL

16

Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

CD137L/1547

0.1 mg/ml

Other Conjugate

CX3CR1

C-X3-C motif chemokine receptor 1

CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28, CX3C chemokine receptor 1, C-X3-C CKR-1, CMK-BRL-1, CMK-BRL1, G-protein coupled receptor 13, beta chemokine receptor-like 1, chemokine (C-C) receptor-like 1, chemokine (C-X3-C motif) receptor 1, chemokine (C-X3-C) receptor 1, fractalkine receptor

IgG2a

Tumor necrosis factor ligand superfamily member 9

TNFSF9 / 4-1BBL is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9 / 4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9 / 4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. It has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine is required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C,RT

41116100