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IHC-P analysis of human malignant melanoma using GTX01919 CD146 antibody [N1238]. Note membrane staining of metastatic melanocytes and endothelial cells.
IHC-P analysis of human malignant melanoma using GTX01919 CD146 antibody [N1238]. Note membrane staining of metastatic melanocytes and endothelial cells.
IHC-P analysis of human malignant melanoma using GTX01919 CD146 antibody [N1238]. Note membrane staining of metastatic melanocytes and endothelial cells.

CD146 antibody [N1238]

GTX01919
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMCAM
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD146 antibody [N1238]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    N1238
  • Conjugate
    Unconjugated
  • Gene ID4162
  • Target name
    MCAM
  • Target description
    melanoma cell adhesion molecule
  • Target synonyms
    CD146, HEMCAM, METCAM, MUC18, MelCAM, cell surface glycoprotein MUC18, Gicerin, S-endo 1 endothelial-associated antigen, cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma-associated antigen A32, melanoma-associated antigen MUC18
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP43121
  • Protein Name
    Cell surface glycoprotein MUC18
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Shi J, Jiao T, Guo Q, et al. A Cell Surface-Binding Antibody Atlas Nominates a MUC18-Directed Antibody-Drug Conjugate for Targeting Melanoma. Cancer Res. 2023,83(22):3783-3795. doi: 10.1158/0008-5472.CAN-23-1356
    Read this paper