Immunohistochemistry of paraffin-embedded Human colon using MCAM Polyclonal Antibody at dilution of 1:100 (40x lens).
CD146 Polyclonal Antibody
E-AB-64865
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCD146 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionCD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
- UNSPSC12352203