Bio-Connect

CD151 antibody [11G5a]

GTX75456
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetCD151
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD151 antibody [11G5a]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1/100. FACS: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    11G5a
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID977
  • Target name
    CD151
  • Target description
    CD151 molecule (Raph blood group)
  • Target synonyms
    CD151 antigen; CD151 antigen (Raph blood group); GP27; hemidesmosomal tetraspanin CD151; membrane glycoprotein SFA-1; MER2; PETA-3; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; platelet-endothelial tetraspan antigen 3; RAPH; SFA1; tetraspanin-24; TSPAN24; tspan-24
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP48509
  • Protein Name
    CD151 antigen
  • Scientific Description
    The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization. Yang XH et al., 2008 May 1, Cancer Res
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