Bio-Connect

CD161 antibody [HP-3G10]

GTX01454
GeneTex
ApplicationsFlow Cytometry, Western Blot, Other Application
Product group Antibodies
TargetKLRB1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD161 antibody [HP-3G10]
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, Western Blot, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    HP-3G10
  • Concentration
    0.5 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3820
  • Target name
    KLRB1
  • Target description
    killer cell lectin like receptor B1
  • Target synonyms
    CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A, killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, killer cell lectin-like receptor subfamily B, member 1, natural killer cell surface protein P1A
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ12918
  • Protein Name
    Killer cell lectin-like receptor subfamily B member 1
  • Scientific Description
    Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

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  • Rodriguez L, Pekkarinen PT, Lakshmikanth T, et al. Systems-Level Immunomonitoring from Acute to Recovery Phase of Severe COVID-19. Cell Rep Med. 2020,1(5):100078. doi: 10.1016/j.xcrm.2020.100078
    Read this paper
  • Schulte-Schrepping J, Reusch N, Paclik D, et al. Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. Cell. 2020,182(6):1419-1440.e23. doi: 10.1016/j.cell.2020.08.001
    Read this paper
  • Sztein MB, Bafford AC, Salerno-Goncalves R. Salmonella enterica serovar Typhi exposure elicits ex vivo cell-type-specific epigenetic changes in human gut cells. Sci Rep. 2020,10(1):13581. doi: 10.1038/s41598-020-70492-2
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  • Guo N, van Unen V, Ijsselsteijn ME, et al. A 34-Marker Panel for Imaging Mass Cytometric Analysis of Human Snap-Frozen Tissue. Front Immunol. 2020,11:1466. doi: 10.3389/fimmu.2020.01466
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  • Gruber CN, Calis JJA, Buta S, et al. Complex Autoinflammatory Syndrome Unveils Fundamental Principles of JAK1 Kinase Transcriptional and Biochemical Function. Immunity. 2020,53(3):672-684.e11. doi: 10.1016/j.immuni.2020.07.006
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  • Cytlak U, Resteu A, Pagan S, et al. Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. Immunity. 2020,53(2):353-370.e8. doi: 10.1016/j.immuni.2020.07.003
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  • Bennstein SB, Weinhold S, Manser AR, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR(+)NKG2A(-) NK cells. Elife. 2020,9. doi: 10.7554/eLife.55232
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  • Sharma M, Zhang S, Niu L, et al. Mucosal-Associated Invariant T Cells Develop an Innate-Like Transcriptomic Program in Anti-mycobacterial Responses. Front Immunol. 2020,11:1136. doi: 10.3389/fimmu.2020.01136
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  • Uchida AM, Boden EK, James EA, et al. Escherichiacoli-Specific CD4+ T Cells Have Public T-Cell Receptors and Low Interleukin 10 Production in Crohn's Disease. Cell Mol Gastroenterol Hepatol. 2020,10(3):507-526. doi: 10.1016/j.jcmgh.2020.04.013
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