CD161, Human (HEK293, Fc)

MedChem Express

CD161, Human (HEK293, Fc)

10

Research Use Only

95.0

KLRB1

killer cell lectin like receptor B1

CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A, killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, killer cell lectin-like receptor subfamily B, member 1, natural killer cell surface protein P1A

Killer cell lectin-like receptor subfamily B member 1

CD161 protein plays a crucial role in inhibiting NK cell toxicity by activating specific acid sphingomyelinase/SMPD1 and increasing ceramide levels. Activation stimulates AKT1/PKB and RPS6KA1/RSK1 kinases, enhancing anti-CD3-induced T cell proliferation. CD161 Protein, Human (HEK293, Fc) is the recombinant human-derived CD161 protein, expressed by HEK293 , with C-hFc labeled tag.

-20°C

41116100