CD162 (Selectin P Ligand) (PSGL1/1601), CF640R conjugate, 0.1mg/mL [26628-22-8]

Biotium

CD162 (Selectin P Ligand) (PSGL1/1601), CF640R conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PSGL1/1601

0.1 mg/ml

Other Conjugate

SELPLG

selectin P ligand

CD162; CLA; cutaneous lymphocyte-associated associated antigen; P-selectin glycoprotein ligand 1; PSGL1; PSGL-1

Mouse

IgG1

P-selectin glycoprotein ligand 1

CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203