CD162 (Selectin P Ligand)(PSGL1/1567), 0.2mg/mL [26628-22-8]

Biotium

CD162 (Selectin P Ligand)(PSGL1/1567), 0.2mg/mL [26628-22-8]

9

26628-22-8

Research Use Only

Monoclonal

PSGL1/1567

0.2 mg/ml

SELPLG

selectin P ligand

CD162, CLA, PSGL-1, PSGL1, P-selectin glycoprotein ligand 1, cutaneous lymphocyte-associated associated antigen

Mouse

IgM

P-selectin glycoprotein ligand 1

CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C,RT

41116161