CD169 Polyclonal Antibody
RD70366A
ApplicationsImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Rat
TargetSIGLEC1
Overview
- SupplierReddot Biotech
- Product NameCD169 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.4 mg/ml
- ConjugateUnconjugated
- Gene ID6614
- Target nameSIGLEC1
- Target descriptionsialic acid binding Ig like lectin 1
- Target synonymsCD169; sialic acid binding Ig-like lectin 1, sialoadhesin; sialic acid-binding immunoglobulin-like lectin 1; sialoadhesin; SIGLEC-1; SN
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.SIGLEC1 (Sialic Acid Binding Ig Like Lectin 1) is a Protein Coding gene. Diseases associated with SIGLEC1 include Proliferative Glomerulonephritis and Diffuse Cutaneous Systemic Sclerosis. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD22.
- ReactivityHuman, Rat
- Storage Instruction-20°C
- UNSPSC12352203