CD19 Antibody / B-lymphocyte marker

Biorbyt

CD19 Antibody / B-lymphocyte marker

10

Variations in protocols, secondaries and substrates may require the CD19 antibody to be titered up or down for optimal performance.

Flow Cytometry, ImmunoFluorescence

Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml FACS, IF

Research Use Only

Monoclonal

CVID3/429

Unconjugated

CD19

CD19 molecule

B4, CVID3, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, T-cell surface antigen Leu-12, differentiation antigen CD19

Mouse

IgG1

B-lymphocyte antigen CD19

CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. [Wiki]

Human

-20°C,2°C to 8°C

12352203