CD19 Antibody (clone CVID3/429)

LifeSpan BioSciences

CD19 Antibody (clone CVID3/429)

23

CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.. Flo (0.5 - 1 µg/10E6 cells), IF (0.5 - 1 µg/ml) CD19 is expressed on follicular dendritic cells and B cells. It is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase.

Flow Cytometry, ImmunoFluorescence

Research Use Only

Monoclonal

CVID3/429

0.2 mg/ml

Unconjugated

...

CD19

CD19 molecule

B4, CVID3, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, T-cell surface antigen Leu-12, differentiation antigen CD19

Mouse

IgG1

Human, Monkey

2°C to 8°C

41116161