CD19(CD19/366), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC040366
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetCD19
Overview
- SupplierBiotium
- Product NameCD19(CD19/366), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC19/366
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID930
- Target nameCD19
- Target descriptionCD19 molecule
- Target synonymsB4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CVID3; differentiation antigen CD19; T-cell surface antigen Leu-12
- HostMouse
- IsotypeIgG1
- Protein IDP15391
- Protein NameB-lymphocyte antigen CD19
- Scientific DescriptionCD19 is a transmembrane glycoprotein that contains two extracellular immunoglobulin-like domains. CD19 is present in both benign and malignant B-cells and is considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the inter-follicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, expression of CD19 is continuous throughout B-cell development and through terminal differentiation of B-cells into plasma cells. Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203