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ProductsBack/CD20(B9E9), CF405S conjugate, 0.1mg/mL [26628-22-8]
CD20(B9E9), CF405S conjugate, 0.1mg/mL [26628-22-8]

CD20(B9E9), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040160
Biotium
ApplicationsFunctional Assay, Flow Cytometry, Western Blot
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetMS4A1
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Overview

  • Supplier
    Biotium
  • Product Name
    CD20(B9E9), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Functional Assay, Flow Cytometry, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B9E9
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID931
  • Target name
    MS4A1
  • Target description
    membrane spanning 4-domains A1
  • Target synonyms
    B1; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CVID5; FMC7; LEU-16; leukocyte surface antigen Leu-16; membrane-spanning 4-domains, subfamily A, member 1; S7
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP11836
  • Protein Name
    B-lymphocyte antigen CD20
  • Scientific Description
    Recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V; Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203