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Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004900ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004900ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA004900ESR1HU at dilution of 1:100

CD22 Antibody

CSB-PA004900ESR1HU
Cusabio
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCD22
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Overview

  • Supplier
    Cusabio
  • Product Name
    CD22 Antibody
  • Delivery Days Customer
    20
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID933
  • Target name
    CD22
  • Target description
    CD22 molecule
  • Target synonyms
    B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigen; sialic acid-binding Ig-like lectin 2; SIGLEC2; SIGLEC-2; T-cell surface antigen Leu-14
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP20273
  • Protein Name
    B-cell receptor CD22
  • Scientific Description
    Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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Immunohistochemistry analysis in human spleen and skeletal muscle tissues using HPA024353 antibody. Corresponding CD22 RNA-seq data are presented for the same tissues.
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