Bio-Connect

CD226 antibody [DX11]

GTX76028
GeneTex
ApplicationsFlow Cytometry, ImmunoPrecipitation
Product group Antibodies
ReactivityHuman
TargetCD226
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Overview

  • Supplier
    GeneTex
  • Product Name
    CD226 antibody [DX11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    FACS: 1/25-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoPrecipitation
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    DX11
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10666
  • Target name
    CD226
  • Target description
    CD226 molecule
  • Target synonyms
    adhesion glycoprotein; CD226 antigen; DNAM1; DNAM-1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; PTA1; T lineage-specific activation antigen 1 antigen; TLiSA1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ15762
  • Protein Name
    CD226 antigen
  • Scientific Description
    This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8(+) T cell responses. Banta KL et al., 2022 Mar 8, Immunity
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